Research2022.06.28

【Paper Published】Research Paper Published in Scientific Reports

[【Health and Sports Department】Elucidation of Brain Fatigue Mechanism Induced by Intense Exercise - Demonstrated Involvement of Hypoxic Blood, Expected to Lead to Countermeasure Development - | Topics & News | Niigata University of Health and Welfare](https://www.nuhw.ac.j

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【Health and Sports Department】Elucidation of Brain Fatigue Mechanism Induced by Intense Exercise - Demonstrated Involvement of Hypoxic Blood, Expected to Lead to Countermeasure Development - | Topics & News | Niigata University of Health and Welfare

Elucidation of Brain Fatigue Mechanism Induced by Intense Exercise - Demonstrated Involvement of Hypoxic Blood, Expected to Lead to Countermeasure Development - | TSUKUBA JOURNAL - Medicine & Health

In sports activities, you may have seen or heard about situations where concentration is lost or wrong decisions are made. Students in the Health and Sports Department may have experienced such situations when they were athletes.

We call this exercise-induced decline in cognitive function (attention, concentration, selective judgment, and other prefrontal cortex functions) cognitive fatigue, and have been investigating its mechanism.

From previous research, we developed an experimental model in which cognitive fatigue occurs by exercising for only 10 minutes in a hypoxic environment using hypoxic gas (13% oxygen concentration) that simulates a high-altitude environment equivalent to 3,500m (Ochi et al., NeuroImage, 2018).

In this study, it was demonstrated that the decrease in arterial oxygen saturation (SpO2) (hypoxic blood) that occurs during exercise is involved as a mechanism of cognitive fatigue caused by exercise in this hypoxic environment.