Research
Exploring "Conditioning" to Maximize
Human Performance
Research Philosophy
"Sports Science through Experience, Trials, and Contribution"
Our laboratory emphasizes field experience, conducts scientifically-based trials, and contributes findings to society. We have developed innovative assessment methods including analysis of accumulated hormones in hair for long-term stress evaluation and prediction of arousal states through facial expression changes. From brain function measurement using fNIRS/fMRI to elucidating the relationship between exercise and cognition, to verification of new training methods using VR technology, we employ multifaceted approaches to achieve performance enhancement and well-being for everyone, from top athletes to the general public.
Three Research Areas
Body
Physical
Evaluating exercise fatigue and training stress in female athletes using physiological indicators such as hair stress factors (cortisol) and peripheral blood lactate. Scientifically elucidating the effects of foam rolling on lactate clearance promotion and exercise under hypoxic conditions on physical function to propose optimal conditioning methods.
Mind
Mental
Visualizing long-term chronic stress and mental health that could not be evaluated conventionally through measurement of cortisol and oxytocin in hair. Elucidating the mechanism of cognitive fatigue from exercise under hypoxic conditions (involvement of peripheral blood lactate), while also working on developing new technology to predict arousal states from facial expression changes during exercise.
Technique
Technical
Demonstrating the effects of VR exercise on working memory and positive mood. Clarifying the relationship between pitch selection ability and spatial executive function in baseball to provide scientific evidence for batting performance improvement. Using fNIRS and fMRI brain activity measurement to elucidate the connection between skill improvement and cognitive function at the brain level.
Fatigue Prevention and Cognitive Function Enhancement
Integrated Understanding of Exercise, Environment, and Cognitive Function
Exercise significantly affects not only muscle and cardiopulmonary function but also cognitive functions (executive function, working memory, attention). Our laboratory has demonstrated that VR exercise improves working memory and positive mood (Mental Health and Physical Activity, 2024). We are also working on developing new technology to predict brain fatigue states from facial expression changes during exercise.
On the other hand, we revealed that the cognitive enhancement effect of exercise is weakened under hypoxic conditions (NeuroImage, 2018), and identified that the cause is hypoxemia during exercise (Scientific Reports, 2022). Currently, we are verifying the common physiological factors between peripheral and central in cognitive fatigue through collaborative research with University of Tsukuba ARIHHP.
Measurement Equipment
Research Objectives
Identifying optimal exercise conditions and establishing intervention methods for exercise-induced and cognitive fatigue in athletes

Performance Maximization

Conditioning Assessment Using Innovative Biomarkers
Our laboratory was the first in the world to demonstrate that hair cortisol can serve as a physiological indicator of training stress in female soccer players (European Journal of Applied Physiology, 2024). We are also advancing research on chronic stress assessment using novel biomarkers such as hair oxytocin.
We have also developed a mental health assessment method using heart rate variability (HRV) for top wheel gymnastics athletes (Applied Psychophysiology and Biofeedback, 2023). In terms of recovery, we have demonstrated that foam rolling improves lactate clearance after high-intensity exercise (Sports, 2024).
🏆Research Participants to Date
- •University Student Athletes
- •Japanese National Wheel Gymnastics Athletes
- •Japanese Women's Basketball Top League Players
💡Innovative Assessment Methods
Developing assessment methods using novel biomarkers such as hair and facial expressions
Research Achievements
Research Achievements
Innovative Assessment Methods
Enabling evaluation of long-term stress and mental health that could not be measured conventionally through hair cortisol and oxytocin analysis
VR Technology Application
Exploring new possibilities in sports science by measuring cognitive function and validating training effects using virtual reality environments
Brain Function Visualization
Using fNIRS and fMRI to elucidate the relationship between exercise and cognitive function at the brain level, proposing evidence-based training methods
Collaborative Research with Elite Athletes
Creating practical insights relevant to the field through collaborative research with Olympic and World Championship-level Japanese national team athletes
Major Publications
Hair Hormones and Heart Rate Variability as Chronic Stress Biomarkers in a Female Long-Distance Runner: A 22-Month Longitudinal Case Study
Research Square (preprint)
DOI: 10.21203/rs.3.rs-7872377/v1Pitch Selection Ability and Spatial Executive Function Independently Predict Baseball Batting Performance
Sports
DOI: 10.3390/sports13100367Facial Lower-Region Changes During High-Intensity Exercise as Predictors of Reduced Arousal State
PsyArXiv (preprint)
DOI: 10.31234/osf.io/6dbhj_v1Oxytocin may reduce the accumulation and effects of chronic stress: An exploratory study using hair samples
bioRxiv (preprint)
DOI: 10.1101/2025.04.15.649015Foam Rolling Intervention Improves Lactate Clearance After High-Intensity Exercise
Sports
DOI: 10.3390/sports12110303Exercising with virtual reality is potentially better for the working memory and positive mood than cycling alone
Mental Health and Physical Activity
DOI: 10.1016/j.mhpa.2024.100641Hair cortisol is a physiological indicator of training stress for female footballers
European Journal of Applied Physiology
DOI: 10.1007/s00421-024-05571-7The Potential of Heart Rate Variability Monitoring for Mental Health Assessment in Top Wheel Gymnastics Athletes: A Single Case Design
Applied Psychophysiology and Biofeedback
DOI: 10.1007/s10484-023-09585-3Cognitive fatigue due to exercise under normobaric hypoxia is related to hypoxemia during exercise
Scientific Reports
DOI: 10.1038/s41598-022-14146-5The Effects of Acute Virtual Reality Exergaming on Mood and Executive Function
JMIR Serious Games
DOI: 10.2196/38200Neural basis for reduced executive performance with hypoxic exercise
NeuroImage
DOI: 10.1016/j.neuroimage.2017.12.091Hypoxia-induced lowered executive function depends on arterial oxygen desaturation
The Journal of Physiological Sciences
DOI: 10.1007/s12576-018-0603-yOngoing Research Projects
健全な発達を促す身体活動に向けた毛髪中コルチゾールによる慢性ストレス評価法確立
Funding Agency: 日本学術振興会
Type: 挑戦的研究(開拓)
運動誘発性末梢血乳酸上昇による前頭前野乳酸上昇が認知疲労に関わるか
Funding Agency: 筑波大学ARIHHP
Type: 共同利用・共同研究
運動による実行機能低下の神経機構の解明 - 脳内乳酸濃度の役割
Funding Agency: 明治安田厚生事業団
Type: 若手研究者のための健康科学研究助成
運動による実行機能低下の生理機構: 末梢血乳酸がバイオマーカーとなりうるか
Funding Agency: カシオ科学振興財団
Type: 研究助成
For Those Interested in Our Laboratory
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